Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions

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Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions

Low-grade cytological abnormalities of the cervix can be challenging to manage; while most will clear without intervention, between 10% and 20% could harbour high-grade lesions. Furthermore, low-grade abnormalities represent the largest category of abnormal results. In Scotland, of the 409 000 cervical screening tests that were performed in 2011–2012, 90.9% had a negative result, 1.3% had high-...

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Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions.

BACKGROUND Atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intra-epithelial lesions (LSIL) are minor lesions of the cervical epithelium, detectable by cytological examination of cells collected from the surface of the cervix of a woman.Usually, women with ASCUS and LSIL do not have cervical (pre-) cancer, however a substantial proportion of them do have under...

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Triage of Women with Low-Grade Cervical Lesions - HPV mRNA Testing versus Repeat Cytology

BACKGROUND In Norway, women with low-grade squamous intraepithelial lesions (LSIL) are followed up after six months in order to decide whether they should undergo further follow-up or be referred back to the screening interval of three years. A high specificity and positive predictive value (PPV) of the triage test is important to avoid unnecessary diagnostic and therapeutic procedures. MATER...

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Repeat Cytology and Human Papillomavirus Screening Strategies in Detecting Preinvasive Cervical Lesions

The aim of the present study was to determine the value of human papillomavirus (HPV) testing in screening patients with preinvasive cervical lesions. Seven hundred thirty-four women diagnosed with atypical squamous cells of undetermined significance (ASCUS+) cervical cytology during routine screening had additional cytologic testing and HPV DNA testing within 6 months of their diagnosis, after...

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Fine Needle Aspiration Cytology versus Fine Needle Capillary Sampling in Cytological Diagnosis of Thyroid Lesions

Background and Objectives: Fine needle aspiration cytology (FNAC) is an established out- patient procedure used in primary diagnosis of palpable thyroid lesions. A modified technique fine needle capillary sampling (FNCS) obviates the need of suction, is less painful, patient friendly and reported to overcome the problem of inadequate and bloody specimens. The aim of our study was to compare the...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2013

ISSN: 1465-1858

DOI: 10.1002/14651858.cd008054.pub2